Overview

There has been a significant improvement in the quality of clinical research performed in the field of neuromodulation over the last 40 years. Simple observational and retrospective studies have largely been replaced with prospective, randomized trials as the current level of medical evidence demands. That being said, recently published studies continue to have multiple significant biases, suboptimal outcomes assessments and lack sufficient follow-up. This has been the focus of much recently published research and expert research recommendations. Those in the field of neuromodulation involved in the design or execution of future studies need to be aware of these issues and recommendations. Furthermore, neuromodulation practitioners need to be aware of these issues and recommendations to be able to properly assess the design and quality of execution of these important future studies

Program

Moderators: Robert M. Levy, MD, PhD and Christopher J. Gilligan, MD, MBA
Presenters: Ahish Chitneni DO, Gloria Seah MD, Maria Grabnar MD
Article Authors: Erkan Kurt MD, Simon Thomson MBBS FRCA FIPP FFPMRCA and Milan Obradovic MBiomedE.

Lectures:

1.) Research Design Considerations for Randomized Controlled Trials of Spinal Cord Stimulation for Pain: Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials/Institute of Neuromodulation/International Neuromodulation Society Recommendations
2.) Randomized Placebo-/Sham-Controlled Trials of Spinal Cord Stimulation: A Systematic Review and Methodological Appraisal
3.) Current Status of SCS Clinical Trials Standards - 4 Years after IMMPACT/IoN/INS Conference

Learning Objectives

Upon completing this webinar attendees will be able to:

1.) Paz-Solís J, Thomson S, Jain R, Chen L, Huertas I, Doan Q. Exploration of High- and Low-Frequency Options for Subperception Spinal Cord Stimulation Using Neural Dosing Parameter Relationships: The HALO Studyץ
2.) Kurt E, Noordhof RK, van Dongen R, Vissers K, Henssen D, Engels Y. Spinal Cord Stimulation in Failed Back Surgery Syndrome: An Integrative Review of Quantitative and Qualitative Studies.
3.) Falowski SM, Kim CH, Obradovic M, Parker JL. A Prospective Multicenter Case Series Utilizing Intraoperative Neuromonitoring With Evoked Compound Action Potentials to Confirm Spinal Cord Stimulation Lead Placement.